Three strangers who share an obsession with true crime suddenly find themselves wrapped up in one.

The Mantle twins, identical from head to toe, are on a mission to change the way women give birth.

Pakistan-born comedian Kumail Nanjiani and grad student Emily Gardner fall in love but struggle as their cultures clash. When Emily contracts a mysterious illness, Kumail finds himself forced to face her feisty parents, his family's expectations, and his true feelings.