A virus has decimated humankind. Those who survived emerged blind. Centuries later when twins are born with the mythic ability to see, their father must protect his tribe against a threatened queen.

Lucy Jacobs is a small-town girl who has started her freshman year at a big-city university. When Lucy returns home for Thanksgiving break, she suspects she is about to get turkey dropped: dumped by her high school sweetheart.

Scientist Will Rodman is determined to find a cure for Alzheimer's, the disease which has slowly consumed his father. Will feels certain he is close to a breakthrough and tests his latest serum on apes, noticing dramatic increases in intelligence and brain activity in the primate subjects – especially Caesar, his pet chimpanzee.