Reze-Tiana Wessels was born in Durban, KwaZulu-Natal and grew up in Sandton, South Africa. She is one of three siblings to parents Pieter Wessels and Sanette Wessels (née Joubert). Reze-Tiana is of Afrikaner descent with some German, Dutch, French, Italian and Irish heritage. Reze-Tiana finished high school at Hoërskool Randburg in 2015 and furthered her drama studies at the Performing Arts Lifestyle Institute (PALI) in Pretoria, South Africa where she graduated in 2018. She is well trained in Ballet, Modern, Contemporary, Jazz, Irish dancing, Ballroom and Latin Dancing. Her first role was in the Afrikaans TV Soap "7de Laan" as Mieke Basson (2021), a recurring character on the famous South African soap drama. In the same year she had supporting roles in four other KykNet TV Films, "Tjops vir Brekvis", "Alomtjom", "Madelein" and "Lykskou". Reze-Tiana made her international debut in the remake film, Slumber Party Massacre (2021) in which she played the role of Ashley.