Dree Louise Hemingway Crisman was born in Sun Valley, Idaho. She is the daughter of actress Mariel Hemingway and Stephen Crisman, as well as the niece of the late model and actress Margaux Hemingway. Author Ernest Hemingway is her maternal great-grandfather. She has a younger sister named Langley Fox Hemingway Crisman (known as Langley Fox). She grew up in Ketchum, Idaho and attended Ernest Hemingway Elementary School. She later moved to California and lived in the Westlake Village. She attended Oaks Christian High School for two and a half years and then dropped out to pursue her modeling career. She was presented as a debutante at the Bal des débutantes in Paris, France in 2003. Hemingway has represented major companies in print advertising as well as in fashion shows. In March 2009, she debuted at the fall/winter 09-10 catwalk show for Givenchy in Paris. In June 2009, she walked in the Calvin Klein resort show in New York. In September 2009, she opened the Topshop spring/summer 2010 show in London. In January 2010, she became the new face of the Gianfranco Ferré advertising campaign. Later that year, she fronted a new advertising campaign for the Salvatore Ferragamo perfume Attimo. She was photographed by Bryan Adams for the spring 2011 issue of Zoo Magazine. Hemingway has also walked for Shiatzy Chen, House of Holland, Karl Lagerfeld, Giles, Chanel, and Rue du Mail shows. She has also done campaigns for Gucci, Jean Paul Gaultier, Valentino, H&M, Chanel, Paco Rabanne, and A.Y. Not Dead. She has also done editorials for Harper's Bazaar, i-D, V, W, Numéro, and multiple national editions of Vogue. Hemingway starred in the U.S. independent film Starlet (2012), directed by Sean Baker. She, along with the rest of the cast, was awarded the Robert Altman Award for the film at the 2012 Independent Spirit Awards. She has since had supporting roles in films such as Listen Up Philip (2014) and While We're Young (2014). She appeared in the music video for "I Always Knew", a single from The Vaccines' album, "Come of Age".