A robot apocalypse put the brakes on their cross-country road trip. Now it’s up to the Mitchells — the world’s weirdest family — to save the human race.

Gene, a multi-expressional emoji, sets out on a journey to become a normal emoji.

After the disastrous food storm in the first film, Flint and his friends are forced to leave the town. Flint accepts the invitation from his idol Chester V to join The Live Corp Company, which has been tasked to clean the island, and where the best inventors in the world create technologies for the betterment of mankind. When Flint discovers that his machine still operates and now creates mutant food beasts like living pickles, hungry tacodiles, shrimpanzees and apple pie-thons, he and his friends must return to save the world.

Boog's friends rally to bring him home from a Russian traveling circus.