In Japan in the year 1600, at the dawn of a century-defining civil war, Lord Yoshii Toranaga is fighting for his life as his enemies on the Council of Regents unite against him, when a mysterious European ship is found marooned in a nearby fishing village.

I Origins follows a molecular biologist studying the evolution of the human eye. He finds his work permeating his life after a brief encounter with an exotic young woman who slips away from him. As his research continues years later with his lab partner, they make a stunning scientific discovery that has far reaching implications and complicates both his scientific and and spiritual beliefs. Traveling half way around the world, he risks everything he has ever known to validate his theory.